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Article

A statistical framework for modeling HLA-dependent T cell response data.

PLoS computational biology - 1 Oct 2007

Listgarten Jennifer, Frahm Nicole, Kadie Carl, Brander Christian, Heckerman David

Abstract excerpt

The identification of T cell epitopes and their HLA (human leukocyte antigen) restrictions is important for applications such as the design of cellular vaccines for HIV. Traditional methods for such identification are costly and time-consuming. Recently, a more expeditious laboratory technique using ELISpot assays has been developed that allows for rapid screening of specific responses. However, this assay does...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17937494
DOI: 10.1371/journal.pcbi.0030188
PMCID: PMC2014793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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