Article
Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan.
PLoS computational biology - 4 Jul 2008
Nielsen Morten, Lundegaard Claus, Blicher Thomas, Peters Bjoern, Sette Alessandro, Justesen Sune, Buus Søren, Lund Ole
Abstract excerpt
CD4 positive T helper cells control many aspects of specific immunity. These cells are specific for peptides derived from protein antigens and presented by molecules of the extremely polymorphic major histocompatibility complex (MHC) class II system. The identification of peptides that bind to MH...
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