Article
Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8 T-cell responses.
Immunology - 1 Apr 2010
Axelsson-Robertson Rebecca, Weichold Frank, Sizemore Donata, Wulf Markus, Skeiky Yasir A W, Sadoff Jerry, Maeurer Markus J
Abstract excerpt
The molecular definition of major histocompatibility complex (MHC) class I-presented CD8(+) T-cell epitopes from clinically relevant Mycobacterium tuberculosis (Mtb) target proteins will aid in the rational design of T-cell-based diagnostics of tuberculosis (TB) and the measurement of TB vaccine-...
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