Article
Genome-wide association analysis identifies a GLUL haplotype for familial hepatitis B virus-related hepatocellular carcinoma.
Cancer - 15 Oct 2017
Lin You-Yu, Yu Ming-Whei, Lin Shi-Ming, Lee Shou-Dong, Chen Chih-Ling, Chen Ding-Shinn, Chen Pei-Jer
Abstract excerpt
BACKGROUND: A family history of liver cancer increases the risk of developing hepatocellular carcinoma (HCC) by 2-fold to 10-fold among patients with chronic hepatitis B virus (HBV). Previous genome-wide association studies have identified many possible susceptible loci associated with sporadic HBV-related HCC. However, despite family history being a well-known risk factor for HBV-related HCC, to the authors'...
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