Article
UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma.
Journal of viral hepatitis - 1 Nov 2018
Liu Yao, Song Ci, Ni Hengli, Jiao Weijuan, Gan Wenjuan, Dong Xiaoqiang, Liu Jibin, Zhu Liguo, Zhai Xiangjun, Hu Zhibin, Li Jianming
Abstract excerpt
Previously, we identified UBE2L3 as a susceptibility gene for chronic hepatitis B virus (HBV) infection through genome-wide association study. Here, we analysed the association between genetic variants of UBE2L3 and the susceptibility to HBV-related hepatocellular carcinoma (HCC) and further explored its role in HCC. This case-control study included 1344 subjects who cleared HBV, 1560 HBV carriers and 1057...
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