Article
Genetic association of polymorphisms at the intergenic region between PRDM1 and ATG5 with hepatitis B virus infection in Han Chinese patients.
Journal of medical virology - 1 Aug 2020
Li Na, Fan Xiude, Wang Xiaoyun, Zhang Xiaoge, Zhang Kun, Han Qunying, Lv Yi, Liu Zhengwen
Abstract excerpt
Chronic hepatitis B virus (HBV) infection is related to chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC), and the interplay between the virus and host immune response leads to different outcomes of the infection. PR domain zinc finger protein 1 (PRDM1) and autophagy-related protein 5 (ATG5) are involved in immune response and HBV infection. An intergenic region between PRDM1 and ATG5 (PRDM1-ATG5...
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