Article
Single nucleotide polymorphisms associated with hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
Intervirology - 1 Jan 2005
Kim Yoon Jun, Lee Hyo-Suk
Abstract excerpt
It is estimated that there are millions of single nucleotide polymorphisms (SNPs) within human genome and there are likely to explain much of the genetic diversity of individuals. Hepatocellular carcinoma (HCC) is etiologically associated with hepatitis B virus (HBV) in 80% of cases, and is the dominant cause of death among HBV carriers. Among patients with chronic HBV infection, family history is a known risk...
Topics
- Carcinoma, Hepatocellular
- Female
- Genetic Predisposition to Disease
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Neoplasms
- Male
- Molecular Epidemiology
- Polymorphism, Single Nucleotide
