Article
Genetic Susceptibility to Hepatocellular Carcinoma in Patients with Chronic Hepatitis Virus Infection.
Viruses - 17 Feb 2023
Yang Tsai-Hsuan, Chan Chi, Yang Po-Jiun, Huang Yu-Han, Lee Mei-Hsuan
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths globally. The risk factors for HCC include chronic hepatitis B and C virus infections, excessive alcohol consumption, obesity, metabolic disease, and aflatoxin exposure. In addition to these viral and environmental risk factors, individual genetic predisposition is a major determinant of HCC risk. Familial clustering of HCC has...
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