Article
Genome-wide association study of chronic hepatitis B virus infection reveals a novel candidate risk allele on 11q22.3.
Journal of medical genetics - 1 Nov 2013
Al-Qahtani Ahmed, Khalak Hanif G, Alkuraya Fowzan S, Al-hamoudi Waleed, Al-hamoudy Waleed, Alswat Khalid, Al Balwi Mohammed A, Al Abdulkareem Ibrahim, Sanai Faisal M, Abdo Ayman A
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) affects millions of people worldwide. While some people are able to clear the virus following the first encounter, those who develop chronic infection manifest remarkable clinical heterogeneity that ranges from asymptomatic carrier state to cirrhosis and hepatocellular carcinoma. Despite extensive studies, little is known about genetic host factors that influence the outcome of...
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