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Article

Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer.

Oncotarget - 4 Jul 2017

Wang Yuan, Hao Da-Peng, Li Jing-Jing, Wang Li, Di Li-Jun

Abstract excerpt

Enhancer is critical cis regulatory elements in gene expression. To understand whether and how the aberrant enhancer activation may contribute to cancer risk, the differentially methylated enhancers (eDMRs) in normal and malignant breast tissues were identified and analyzed. By incorporating genome-wide chromatin interaction, integrated analysis of eDMRs and target gene expression identified 1,272...

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Identifiers

PMID: 28621677
DOI: 10.18632/oncotarget.18348
PMCID: PMC5546512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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