Article
The complexity of epigenetic diseases.
The Journal of pathology - 1 Jan 2016
Brazel Ailbhe Jane, Vernimmen Douglas
Abstract excerpt
Over the past 30 years, a plethora of pathogenic mutations affecting enhancer regions and epigenetic regulators have been identified. Coupled with more recent genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) implicating major roles for regulatory mutations in disease, it is clear that epigenetic mechanisms represent important biomarkers for disease development and perhaps even...
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