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Article

Neuropeptide Y expression marks partially differentiated β cells in mice and humans

14 Jun 2017

Abstract excerpt

β Cells are formed in embryonic life by differentiation of endocrine progenitors and expand by replication during neonatal life, followed by transition into functional maturity. In this study, we addressed the potential contribution of neuropeptide Y (NPY) in pancreatic β cell development and maturation. We show that NPY expression is restricted from the progenitor populations during pancreatic development and...

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PMID: 28614797
DOI: 10.1172/jci.insight.94005

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