Article

Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods

2024-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Human endocrine cell differentiation and islet morphogenesis play critical roles in determining islet cell mass and function, but the events and timeline of these processes are incompletely defined. To better understand early human islet cell development and maturation, we collected 115 pediatric pancreata and mapped morphological and spatiotemporal changes from birth through the first ten years...

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Literature Corpus work: 55c189dd-474b-5f2b-9c5a-c5cfd9da2bf2
DOI: 10.1101/2024.12.20.629754

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