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Article

Islet Neogenesis: A Possible Pathway for Beta-Cell Replenishment

1 Jan 2012

Abstract excerpt

Diabetes, particularly type 1 diabetes, results from the lack of pancreatic β-cells. β-cell replenishment can functionally reverse diabetes, but two critical challenges face the field: 1. protection of the new β-cells from autoimmunity and allorejection, and 2. development of β-cells that are readily available and reliably functional. This chapter will examine the potential of endogenous replenishment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23804276
DOI: 10.1900/rds.2012.9.407

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