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Article

The Development of Beta-cell Mass: Recent Progress and Potential Role of GLP-1

1 Nov 2004

Abstract excerpt

Over the last decade, remarkable strides in incretin hormone biology have laid the foundation for our more recent appreciation that GLP-1 not only regulates mature beta-cell function but also critically regulates beta-cell differentiation, beta-cell proliferation and beta-cell survival. Dysregulated beta-cell growth and function are central to the pathophysiology of both type 1 and type 2 diabetes. Thus, GLP-1...

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PMID: 15655713
DOI: 10.1055/s-2004-826168

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