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Article

Tumor diversity and evolution revealed through RADseq.

Oncotarget - 27 Jun 2017

Perry Elizabeth B, Makohon-Moore Alvin, Zheng Caihong, Kaufman Charles K, Cai Jun, Iacobuzio-Donahue Christine A, White Richard M

Abstract excerpt

Cancer is an evolutionary disease, and there is increasing interest in applying tools from evolutionary biology to understand cancer progression. Restriction-site associated DNA sequencing (RADseq) was developed for the field of evolutionary genetics to study adaptation and identify evolutionary relationships among populations. Here we apply RADseq to study tumor evolution, which allows for unbiased sampling of...

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Identifiers

PMID: 28611298
DOI: 10.18632/oncotarget.18355
PMCID: PMC5522028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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