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Article

The Evolutionary Forest of Pancreatic Cancer

8 Oct 2024

Abstract excerpt

Abstract The genomic features of pancreatic ductal adenocarcinoma (PDAC) have been well described, yet the evolutionary contexts within which these features occur remain unexplored. We studied genome landscapes, phylogenies, and clonal compositions of 91 PDACs in relation to clinicopathologic features. There was no difference in the number of driver mutations or evolutionary timing when each mutation occurred....

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PMID: 39378050
DOI: 10.1158/2159-8290.cd-23-1541

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