Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of putative efflux pump genes to isoniazid resistance in clinical isolates of Mycobacterium tuberculosis

1 Jan 2017

Abstract excerpt

BACKGROUND: Isoniazid (INH) resistance in Mycobacterium tuberculosis has been mainly attributed to mutations in katG (64%) and inhA (19%). However, 20%-30% resistance to INH cannot be explained by mutations alone. Hence, other mechanisms besides mutations may play a significant role in providing drug resistance. Here, we explored the role of 24 putative efflux pump genes conferring INH-resistance in M....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diagnosis and treatment of tuberculosis
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28559521
DOI: 10.4103/ijmy.ijmy_26_17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of putative efflux pump genes to isoniazid resistance in clinical isolates of Mycobacterium tuberculosisPMID 28559521Read ↗

Efflux Pump Gene Expression in Multidrug-Resistant Mycobacterium tuberculosis Clinical IsolatesSemantic proximity Read ↗

Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Prevalence of mutations in genes associated with isoniazid resistance in Mycobacterium tuberculosis isolates from re-treated smear-positive pulmonary tuberculosis patients: A meta-analysis.Semantic proximity Read ↗

Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities.Semantic proximity Read ↗

Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USASemantic proximity Read ↗

Detecting novel genetic variants associated with isoniazid-resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

Detection and characterization of mutations in genes related to isoniazid resistance in Mycobacterium tuberculosis clinical isolates from Iran.Semantic proximity Read ↗

Overview on mechanisms of isoniazid action and resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Evaluation of efflux pump gene expression among drug susceptible and drug resistant strains of Mycobacterium tuberculosis from Iran.Semantic proximity Read ↗

Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Whole genome sequencing of isoniazid monoresistant clinical isolates of Mycobacterium tuberculosis reveals novel genetic polymorphisms.Semantic proximity Read ↗

Overexpression of efflux pump genes is one of the mechanisms causing drug resistance in Mycobacterium tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.