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Overexpression of efflux pump genes is one of the mechanisms causing drug resistance in Mycobacterium tuberculosis

4 Dec 2023

Abstract excerpt

ABSTRACT Currently, drug resistance is a formidable obstacle to tuberculosisprevention globally. A deep understanding of the drug-resistance mechanism of Mycobacterium tuberculosis is helpful to deal with this problem. In this study, 46 clinical isolates of Mycobacterium tuberculosis from Zigong, Sichuan, China, including 5 sensitive isolates, 5 rifampicin (RIF) mono-resistant isolates, 18 isoniazid...

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PMID: 38047702
DOI: 10.1128/spectrum.02510-23

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