Article
Butyrate and retinoic acid imprint mucosal-like dendritic cell development synergistically from bone marrow cells.
Clinical and experimental immunology - 1 Sept 2017
Qiang Y, Xu J, Yan C, Jin H, Xiao T, Yan N, Zhou L, An H, Zhou X, Shao Q, Xia S
Abstract excerpt
Accumulating data show that the phenotypes and functions of distinctive mucosal dendritic cells (DCs) in the gut are regulated by retinoic acid (RA). Unfortunately, the exact role of butyrate in RA-mediated mucosal DC differentiation has not been elucidated thoroughly to date. Mucosal-like dendritic cell differentiation was completed in vitro by culturing bone marrow cells with growth factors...
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