Article
Continuous retinoic acid induces the differentiation of mature regulatory monocytes but fails to induce regulatory dendritic cells.
BMC immunology - 18 Feb 2014
VanGundy Zachary C, Guerau-de-Arellano Mireia, Baker Julie D, Strange Heather R, Olivo-Marston Susan, Muth Dillon C, Papenfuss Tracey L
Abstract excerpt
BACKGROUND: Myeloid cells (MC) have potent immunoregulatory abilities that can be therapeutically useful to treat inflammatory disease. However, the factors which promote regulatory myeloid cell differentiation remain poorly understood. We have previously shown that estriol (E3) induces mature regulatory dendritic cells in vivo. To determine whether additional steroid hormones could induce mature regulatory...
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