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Article

Increased production of IFN-γ by natural killer cells triggered with bone marrow-derived dendritic cells cultured in the presence of retinoic acid.

European journal of pharmacology - 5 Sept 2013

Chau Jessie, Moza Dasha, Hossain Nazia, Lee Jeffrey K, Bienenstock John, Karimi Khalil

Abstract excerpt

All-trans-retinoic acid (RA), a vitamin A metabolite, is beginning to be explored as an immunopharmacologic agent. While its effects on dendritic cells and the induction of regulatory T cells have been recognized, little is known about the effect of RA on dendritic cell-natural killer cell (DC-NK) crosstalk. DC-NK crosstalk is important in directing the innate immune response, as well as subsequent adaptive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23701916
DOI: 10.1016/j.ejphar.2013.04.050

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