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Article

A Comparison of Two-Stage Approaches Based on Penalized Regression for Estimating Gene Networks.

Journal of computational biology : a journal of computational molecular cell biology - 1 Jul 2017

Lee Minhyeok, Seok Junhee, Tae Donghyun, Zhong Hua, Han Sung Won

Abstract excerpt

Graphical models are commonly used for illustrating gene networks. However, estimating directed networks are generally challenging because of the limited sample size compared with the dimensionality of an experiment. Many previous studies have provided insight into the problem, and recently, two-stage approaches have shown significant improvements for estimating directed acyclic graphs. These two-stage approaches...

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PMID: 28541712
DOI: 10.1089/cmb.2017.0052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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