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Article

Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene interaction in a case-control study.

BMC medical genetics - 4 Dec 2009

He Hua, Oetting William S, Brott Marcia J, Basu Saonli

Abstract excerpt

BACKGROUND: There is a growing awareness that interaction between multiple genes play an important role in the risk of common, complex multi-factorial diseases. Many common diseases are affected by certain genotype combinations (associated with some genes and their interactions). The identification and characterization of these susceptibility genes and gene-gene interaction have been limited by small sample size...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19961594
DOI: 10.1186/1471-2350-10-127
PMCID: PMC2800840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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