Article
Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence.
PLoS pathogens - 1 May 2017
Barczak Amy K, Avraham Roi, Singh Shantanu, Luo Samantha S, Zhang Wei Ran, Bray Mark-Anthony, Hinman Amelia E, Thompson Matthew, Nietupski Raymond M, Golas Aaron, Montgomery Paul, Fitzgerald Michael, Smith Roger S, White Dylan W, Tischler Anna D, Carpenter Anne E, Hung Deborah T
Abstract excerpt
A key to the pathogenic success of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is the capacity to survive within host macrophages. Although several factors required for this survival have been identified, a comprehensive knowledge of such factors and how they work together to manipulate the host environment to benefit bacterial survival are not well understood. To systematically...
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