Article

<i>Mycobacterium tuberculosis</i> diversity and macrophage heterogeneity dictate phagosomal acidification

2025-11-19

Abstract excerpt

<h4>ABSTRACT</h4> Therapies counteracting pathogen-induced immune modulation of the host responses represent a promising improvement for tuberculosis treatments. Despite the documented role of host immune heterogeneity and bacterial genotypic background in determining infection outcomes, their interplay remains largely uncharacterized. We investigate the Mycobacterium tuberculosis (MTB)-human macrophage interact...

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Literature Corpus work: 70e8e535-2c07-5219-8e7b-e7b6b1fccfd2
DOI: 10.1101/2025.11.19.689035

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