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Article

Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.

PloS one - 10 Dec 2010

Beaulieu Aimee M, Rath Poonam, Imhof Marianne, Siddall Mark E, Roberts Julia, Schnappinger Dirk, Nathan Carl F

Abstract excerpt

In spite of its highly immunogenic properties, Mycobacterium tuberculosis (Mtb) establishes persistent infection in otherwise healthy individuals, making it one of the most widespread and deadly human pathogens. Mtb's prolonged survival may reflect production of microbial factors that prevent even more vigorous immunity (quantitative effect) or that divert the immune response to a non-sterilizing mode...

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Identifiers

PMID: 21170273
DOI: 10.1371/journal.pone.0015120
PMCID: PMC3000826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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