Article
A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening.
Journal of visualized experiments : JoVE - 17 Jan 2014
Queval Christophe J, Song Ok-Ryul, Delorme Vincent, Iantomasi Raffaella, Veyron-Churlet Romain, Deboosère Nathalie, Landry Valérie, Baulard Alain, Brodin Priscille
Abstract excerpt
Despite the availability of therapy and vaccine, tuberculosis (TB) remains one of the most deadly and widespread bacterial infections in the world. Since several decades, the sudden burst of multi- and extensively-drug resistant strains is a serious threat for the control of tuberculosis. Therefore, it is essential to identify new targets and pathways critical for the causative agent of the tuberculosis,...
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