Article
Partially compromised specification causes stochastic effects on gut development in C. elegans.
Developmental biology - 1 Jul 2017
Choi Hailey, Broitman-Maduro Gina, Maduro Morris F
Abstract excerpt
The C. elegans gut descends from the E progenitor cell through a series of stereotyped cell divisions and morphogenetic events. Effects of perturbations of upstream cell specification on downstream organogenesis have not been extensively investigated. Here we have assembled an allelic series of strains that variably compromise specification of E by perturbing the activation of the gut-specifying end-1 and end-3...
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