Article
Specific roles for the GATA transcription factors end-1 and end-3 during C. elegans E-lineage development.
Developmental biology - 15 Oct 2011
Boeck Max E, Boyle Tom, Bao Zhirong, Murray John, Mericle Barbara, Waterston Robert
Abstract excerpt
end-1 and end-3 are GATA transcription factors important for specifying endoderm cell fate in Caenorhabditis elegans. Deletion of both factors together results in larval arrest, 0% survival and a fate change in the endoderm-specifying E lineage. Individual deletions of either factor, however, result in the development of viable, fertile adults, with 100% of worms developing to adults for end-1(-) and 95% for...
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