Article
A gut-to-pharynx/tail switch in embryonic expression of the Caenorhabditis elegans ges-1 gene centers on two GATA sequences.
Developmental biology - 1 Aug 1995
Egan C R, Chung M A, Allen F L, Heschl M F, Van Buskirk C L, McGhee J D
Abstract excerpt
The Caenorhabditis elegans ges-1 gene (gut esterase No. 1) is expressed only in the intestinal lineage, beginning when the developing gut has only four to eight cells. We analyze the sequence requirements for this tissue-specific gene regulation by injecting deleted/mutated constructs of the ges-...
Topics
- Animals
- Base Sequence
- Caenorhabditis elegans
- DNA, Helminth
- Enhancer Elements, Genetic
- Esterases
- Gene Expression Regulation, Developmental
- Genes, Helminth
- Genetic Markers
- Heat-Shock Proteins
- Intestines
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Pharynx
- Phenotype
- Promoter Regions, Genetic
- Sequence Deletion