Article
Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network.
Developmental biology - 15 Apr 2010
Owraghi Melissa, Broitman-Maduro Gina, Luu Thomas, Roberson Heather, Maduro Morris F
Abstract excerpt
In C. elegans the 4-cell stage blastomere EMS is an endomesodermal precursor. Its anterior daughter, MS, makes primarily mesodermal cells, while its posterior daughter E generates the entire intestine. The gene regulatory network underlying specification of MS and E has been the subject of study for more than 15 years. A key component of the specification of the two cells is the involvement of the...
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