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Article

Genetic and phenotypic studies of hypomorphic lin-12 mutants in Caenorhabditis elegans.

Genetics - 1 Nov 1993

Sundaram M, Greenwald I

Abstract excerpt

The lin-12 gene of Caenorhabditis elegans is thought to encode a receptor for intercellular signals that specify certain cell fates during development. We describe several alleles of lin-12 that reduce but do not eliminate lin-12 activity (hypomorphic alleles). These alleles cause a novel egg-laying defective (Egl) phenotype in hermaphrodites as well as incompletely penetrant cell fate transformations seen with...

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Identifiers

PMID: 8293977
DOI: 10.1093/genetics/135.3.755
PMCID: PMC1205718

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