Combinatorial decoding of the invariant C. elegans embryonic lineage in space and time.

doi:10.1002/dvg.22928

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Article

Combinatorial decoding of the invariant C. elegans embryonic lineage in space and time.

Genesis (New York, N.Y. : 2000) - 1 Apr 2016

Zacharias Amanda L, Murray John Isaac

Abstract excerpt

Understanding how a single cell, the zygote, can divide and differentiate to produce the diverse animal cell types is a central goal of developmental biology research. The model organism Caenorhabditis elegans provides a system that enables a truly comprehensive understanding of this process across all cells. Its invariant cell lineage makes it possible to identify all of the cells in each individual and compare...

Topics

Animals
Body Patterning
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Differentiation
Cell Lineage
Gene Expression Regulation, Developmental
Models, Biological
Phenotype
Signal Transduction
Transcription Factors

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PMID: 26915329
DOI: 10.1002/dvg.22928
PMCID: PMC4840027

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