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Article

Uncoupling different characteristics of the C. elegans E lineage from differentiation of intestinal markers.

PloS one - 1 Jan 2014

Robertson Scott M, Medina Jessica, Lin Rueyling

Abstract excerpt

In the 4-cell C. elegans embryo, a signal from P2 to its anterior sister, EMS, specifies the posterior daughter of EMS, E, as the sole founder cell for intestine. The P2-to-EMS signal restricts high level zygotic expression of the redundant GATA transcription factors, END-1 and END-3, to only the E lineage. Expression of END-1 or END-3 in early blastomeres is sufficient to drive intestinal differentiation. We...

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Identifiers

PMID: 25181289
DOI: 10.1371/journal.pone.0106309
PMCID: PMC4152275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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