Article
Genetic redundancy in endoderm specification within the genus Caenorhabditis.
Developmental biology - 15 Aug 2005
Maduro Morris F, Hill Russell J, Heid Paul J, Newman-Smith Erin D, Zhu Jiangwen, Priess James R, Rothman Joel H
Abstract excerpt
Specification of the endoderm precursor, the E cell, in Caenorhabditis elegans requires a genomic region called the Endoderm Determining Region (EDR). We showed previously that end-1, a gene within the EDR encoding a GATA-type transcription factor, restores endoderm specification to embryos deleted for the EDR and obtained evidence for genetic redundancy in this process. Here, we report molecular identification...
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