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Article

Response of Npt2a knockout mice to dietary calcium and phosphorus.

PloS one - 1 Jan 2017

Li Yuwen, Caballero Daniel, Ponsetto Julian, Chen Alyssa, Zhu Chuanlong, Guo Jun, Demay Marie, Jüppner Harald, Bergwitz Clemens

Abstract excerpt

Mutations in the renal sodium-dependent phosphate co-transporters NPT2a and NPT2c have been reported in patients with renal stone disease and nephrocalcinosis, but the relative contribution of genotype, dietary calcium and phosphate to the formation of renal mineral deposits is unclear. We previously reported that renal calcium phosphate deposits persist and/or reappear in older Npt2a-/- mice supplemented with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28448530
DOI: 10.1371/journal.pone.0176232
PMCID: PMC5407772

Genes

FGF23
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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