Article
The genomic response of the mouse kidney to low-phosphate diet is altered in X-linked hypophosphatemia.
Physiological genomics - 17 Jun 2004
Meyer Martha H, Dulde Emily, Meyer Ralph A
Abstract excerpt
The mechanism for the renal adaptation to low-phosphate diets is not well understood. Whether the Hyp mutation of the Phex gene blocks this adaptation is also not clear. To gain further insight into this, 5-wk-old normal and Hyp mice were fed a control (1.0% P) or low-phosphate diet (0.03% P) for 3-5 days. Renal RNA was hybridized to Affymetrix U74Av2 microarrays (5 arrays/group). Of the 5,719 detectable genes on...
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