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Article

Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development.

American journal of physiology. Renal physiology - 1 Sept 2009

Segawa Hiroko, Onitsuka Akemi, Furutani Junya, Kaneko Ichiro, Aranami Fumito, Matsumoto Natsuki, Tomoe Yuka, Kuwahata Masashi, Ito Mikiko, Matsumoto Mitsuru, Li Minqi, Amizuka Norio, Miyamoto Ken-ichi

Abstract excerpt

Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a rare autosomal recessively inherited disorder, characterized by hypophosphatemia, short stature, rickets and/or osteomalacia, and secondary absorptive hypercalciuria. HHRH is caused by a defect in the sodium-dependent phosphate transporter (NaPi-IIc/Npt2c/NPT2c), which was thought to have only a minor role in renal phosphate (P(i)) reabsorption...

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PMID: 19570882
DOI: 10.1152/ajprenal.00156.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development.PMID 19570882Read ↗

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Response of Npt2a knockout mice to dietary calcium and phosphorus.Semantic proximity Read ↗

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