Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice.

doi:10.1152/ajprenal.00663.2010

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Article

Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice.

American journal of physiology. Renal physiology - 1 Nov 2011

Ohi Akiko, Hanabusa Etsuyo, Ueda Otoya, Segawa Hiroko, Horiba Naoshi, Kaneko Ichiro, Kuwahara Shoji, Mukai Tomo, Sasaki Shohei, Tominaga Rieko, Furutani Junya, Aranami Fumito, Ohtomo Shuichi, Oikawa Yumiko, Kawase Yousuke, Wada Naoko A, Tachibe Takanori, Kakefuda Mami, Tateishi Hiromi, Matsumoto Kaoru, Tatsumi Sawako, Kido Shinsuke, Fukushima Naoshi, Jishage Kou-Ichi, Miyamoto Ken-Ichi

Abstract excerpt

An inorganic phosphate (P(i))-restricted diet is important for patients with chronic kidney disease and patients on hemodialysis. Phosphate binders are essential for preventing hyperphosphatemia and ectopic calcification. The sodium-dependent P(i) (Na/P(i)) transport system is involved in intestinal P(i) absorption and is regulated by several factors. The type II sodium-dependent P(i) transporter Npt2b is...

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PMID: 21816756
DOI: 10.1152/ajprenal.00663.2010

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