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Article

Investigating a case of possible field cancerization in oral squamous cell carcinoma by the use of next-generation sequencing.

Oral oncology - 1 May 2017

Tabatabaeifar Siavosh, Larsen Martin J, Larsen Stine R, Kruse Torben A, Thomassen Mads, Sørensen Jens A

Abstract excerpt

OBJECTIVES: Local recurrence and the development of second primary tumors (SPT) are important factors that can influence the survival rate of oral squamous cell carcinoma (OSCC) patients. We investigate the concept of field cancerization which proposes that normal tissue adjacent to the primary tumor harbor pre-neoplastic alterations that can lead to the development of local recurrence and SPTs. MATERIALS AND...

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PMID: 28438297
DOI: 10.1016/j.oraloncology.2017.03.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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