Article

Spatiotemporal evolution and inter-patient heterogeneity in primary and recurrent/metastatic head and neck squamous cell carcinoma

2023-07-18

Abstract excerpt

<title>Abstract</title> <p>Head and neck cancer squamous cell carcinomas (HNSCCs) are heterogeneous in terms of origin and aetiology. In addition, there is uncertainty about the spatiotemporal genetic evolution from initial diagnosis to recurrence/metastasis (R/M) after primary treatments and further disease progression following systemic treatment. Changes in the genetic profile have implications on the selectio...

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Literature Corpus work: 0c10782d-74ec-5307-96e0-9fea3cf92493
DOI: 10.21203/rs.3.rs-3139047/v1

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