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Article

Multiple-Criteria Decision Analysis-Based Multifactor Dimensionality Reduction for Detecting Gene-Gene Interactions.

IEEE journal of biomedical and health informatics - 1 Jan 2019

Yang Cheng-Hong, Lin Yu-Da, Chuang Li-Yeh

Abstract excerpt

Gene-gene interactions (GGIs) are important markers for determining susceptibility to a disease. Multifactor dimensionality reduction (MDR) is a popular algorithm for detecting GGIs and primarily adopts the correct classification rate (CCR) to assess the quality of a GGI. However, CCR measurement alone may not successfully detect certain GGIs because of potential model preferences and disease complexities. In...

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PMID: 29993963
DOI: 10.1109/JBHI.2018.2790951

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