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Article

Multiobjective multifactor dimensionality reduction to detect SNP-SNP interactions.

Bioinformatics (Oxford, England) - 1 Jul 2018

Yang Cheng-Hong, Chuang Li-Yeh, Lin Yu-Da

Abstract excerpt

Motivation: Single-nucleotide polymorphism (SNP)-SNP interactions (SSIs) are popular markers for understanding disease susceptibility. Multifactor dimensionality reduction (MDR) can successfully detect considerable SSIs. Currently, MDR-based methods mainly adopt a single-objective function (a single measure based on contingency tables) to detect SSIs. However, generally, a single-measure function might not yield...

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PMID: 29471406
DOI: 10.1093/bioinformatics/bty076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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