Article
Identification of multiple gene-gene interactions for ordinal phenotypes.
BMC medical genomics - 1 Jan 2013
Kim Kyunga, Kwon Min-Seok, Oh Sohee, Park Taesung
Abstract excerpt
BACKGROUND: Multifactor dimensionality reduction (MDR) is a powerful method for analysis of gene-gene interactions and has been successfully applied to many genetic studies of complex diseases. However, the main application of MDR has been limited to binary traits, while traits having ordinal features are commonly observed in many genetic studies (e.g., obesity classification - normal, pre-obese, mild obese and...
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