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Article

Weighted pseudolikelihood for SNP set analysis with multiple secondary outcomes in case-control genetic association studies.

Biometrics - 1 Dec 2017

Sofer Tamar, Schifano Elizabeth D, Christiani David C, Lin Xihong

Abstract excerpt

We propose a weighted pseudolikelihood method for analyzing the association of a SNP set, example, SNPs in a gene or a genetic pathway or network, with multiple secondary phenotypes in case-control genetic association studies. To boost analysis power, we assume that the SNP-specific effects are shared across all secondary phenotypes using a scaled mean model. We estimate regression parameters using Inverse...

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Identifiers

PMID: 28346824
DOI: 10.1111/biom.12680
PMCID: PMC5617769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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