Article
Robust analysis of secondary phenotypes in case-control genetic association studies.
Statistics in medicine - 15 Oct 2016
Xing Chuanhua, M McCarthy Janice, Dupuis Josée, Adrienne Cupples L, B Meigs James, Lin Xihong, S Allen Andrew
Abstract excerpt
The case-control study is a common design for assessing the association between genetic exposures and a disease phenotype. Though association with a given (case-control) phenotype is always of primary interest, there is often considerable interest in assessing relationships between genetic exposures and other (secondary) phenotypes. However, the case-control sample represents a biased sample from the general...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
