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Article

Pseudo semiparametric maximum likelihood estimation exploiting gene environment independence for population-based case-control studies with complex samples.

Biostatistics (Oxford, England) - 1 Sept 2012

Li Yan, Graubard Barry I

Abstract excerpt

Advances in human genetics have led to epidemiological investigations not only of the effects of genes alone but also of gene-environment (G-E) interaction. A widely accepted design strategy in the study of how G-E relate to disease risks is the population-based case-control study (PBCCS). For simple random samples, semiparametric methods for testing G-E have been developed by Chatterjee and Carroll in 2005. The...

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Identifiers

PMID: 22522235
DOI: 10.1093/biostatistics/kxs008
PMCID: PMC3616753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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