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Article

Pseudosibship methods in the case-parents design.

Statistics in medicine - 30 Nov 2011

Yu Zhaoxia, Deng Li

Abstract excerpt

Recent evidence suggests that complex traits are likely determined by multiple loci, each of which contributes a weak to moderate individual effect. Although extensive literature exists on multilocus analysis of unrelated subjects, there are relatively fewer strategies for jointly analyzing multiple loci using family data. Here we address this issue by evaluating two pseudosibship methods: the 1:1 matching, which...

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Identifiers

PMID: 21953439
DOI: 10.1002/sim.4397
PMCID: PMC3882162

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