Article
Pseudosibship methods in the case-parents design.
Statistics in medicine - 30 Nov 2011
Yu Zhaoxia, Deng Li
Abstract excerpt
Recent evidence suggests that complex traits are likely determined by multiple loci, each of which contributes a weak to moderate individual effect. Although extensive literature exists on multilocus analysis of unrelated subjects, there are relatively fewer strategies for jointly analyzing multi...
Topics
- Alleles
- Crohn Disease
- Female
- Humans
- Male
- Models, Genetic
- Models, Statistical
- Parents
- Polymorphism, Single Nucleotide
- Quantitative Trait, Heritable
- Regression Analysis
- Research Design
- Siblings