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Article

A General and Robust Framework for Secondary Traits Analysis.

Genetics - 1 Apr 2016

Song Xiaoyu, Ionita-Laza Iuliana, Liu Mengling, Reibman Joan, We Ying

Abstract excerpt

Case-control designs are commonly employed in genetic association studies. In addition to the case-control status, data on secondary traits are often collected. Directly regressing secondary traits on genetic variants from a case-control sample often leads to biased estimation. Several statistical methods have been proposed to address this issue. The inverse probability weighting (IPW) approach and the...

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Identifiers

PMID: 26896329
DOI: 10.1534/genetics.115.181073
PMCID: PMC4827729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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